The Ohio Highway Patrol has not released the name of the motorcyclist, who was pronounced dead at the scene of the approximately 2:15 p.m. crash.
Trooper Crystal Evans said the motorcyclist was heading south on state Route 301 north of the U.S. Route 20 overpass when the accident occurred.
The deer ran in front of a southbound Toyota Prius, was struck by that vehicle and was thrown at the motorcyclist, striking him and knocking him from the motorcycle. The motorcyclist was thrown into the northbound lane and was run over by a Ford Explorer driven by Tim Kader of Carlisle Township, Evans said.
The motorcycle continued to slide down the road and struck a Dodge Stratus driven by Michelle Diaz of Lorain.
Kader said he saw the deer “cartwheel” through the air and the motorcyclist land in front of him. He said he tried to veer off the road to avoid the motorcyclist, but didn’t have enough time to do so.
The driver of the Prius was taken to the hospital for cuts he sustained after glass from his windshield cut him.
Evans said the identity of the motorcyclist, who was not wearing a helmet, was being withheld until his next of kin could be notified.
The deer ran off after the accident, witnesses said.