Ryan is set to hold a rally at an airport in Cincinnati at noon Monday. The first lady will make stops later Monday in Cleveland and near Columbus in Delaware.
Ryan and GOP presidential candidate Mitt Romney campaigned in Ohio on Saturday. Ryan’s rally will mean the Republican ticket has been in Ohio six of the last eight days.
The first lady was last in Ohio on Oct. 2 to speak on the first day of early voting.
Democratic President Barack Obama returns to Ohio Wednesday at Ohio University in Athens, while former President Bill Clinton and music star Bruce Springsteen will campaign Thursday for Obama in Parma.